Document 0806
 DOCN  M94B0806
 TI    Varicella hepatitis: a fatal case in a previously healthy,
       immunocompetent adult. Report of a case, autopsy, and review of the
       literature.
 DT    9412
 AU    Anderson DR; Schwartz J; Hunter NJ; Cottrill C; Bisaccia E; Klainer AS;
       Department of Medicine, Columbia University College of Physicians; and
       Surgeons, New York, NY.
 SO    Arch Intern Med. 1994 Sep 26;154(18):2101-6. Unique Identifier :
       AIDSLINE MED/94379883
 AB    Varicella, usually a benign infection of childhood, is known to be
       associated with more serious complications, especially in adults and
       immunocompromised patients. Of these, varicella pneumonitis is the most
       common. Primary varicella hepatitis has been described, though rarely,
       in immunocompromised patients. We present a case of a previously healthy
       human immunodeficiency virus-negative 26-year-old immigrant from El
       Salvador in whom primary varicella developed that rapidly progressed to
       fulminant hepatic failure, disseminated intravascular coagulation, and
       death. Autopsy revealed evidence of varicella in the liver, adrenal
       glands, and myometrium. To our knowledge, this is the first report of a
       fatal case of varicella hepatitis in a previously healthy,
       immunocompetent patient.
 DE    Adult  Case Report  Chickenpox/*COMPLICATIONS/PATHOLOGY  Disseminated
       Intravascular Coagulation/MICROBIOLOGY  Fatal Outcome  Female  Hepatic
       Encephalopathy/*MICROBIOLOGY/PATHOLOGY  Human  JOURNAL ARTICLE

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